Azulfidine Sulfasalazine and/or alternatives
Azulfidine is used to treat ulcerative colitis. The generic name of the medicine is Sulfasalazine. Azulfidine is a prodrug and not active in indigested form. It is broken down by bacteria in the colon into 5-aminosalicylic acid (5-ASA), and sulfapyridine.
You must buy Azulfidine only as per the prescription of the doctor. The tablet must be taken orally with a full glass of water. Take Azulfidine after food to avoid a stomach upset. Drink lot of fluids during the full course of treatment.
Indications & Dosage of Azulfidine
Azulfidine is a salicylate and it increases the time between the ulcerative colitis attacks. It also decreases inflammation.
The dosage of Azulfidine depends on the medical condition and the response of the patient to treatment. The recommended dosage of Azulfidine is 3 g to 4 g in adults every day. The dosage for children under the age of six is 40-60 mg/kg every day. You must take 3-4 tablets a day depending on the nature of the disease. Take the tablet every eight hours. You may feel well after taking the tablets for a few days. Don’t stop the medication till the course gets over or you will not get the best results. You must take Azulfidine on time. If you miss a dose, take it as soon as possible. If it is time for the next dose, avoid the missed dose. Don’t take an overdose of Azulfidine as it will result in serious side effects. The side effects include seizures, stomach pain, nausea, vomiting and severe dizziness. Seek immediate medical attention in case of an overdose. Don’t share Azulfidine with others.
You must store Azulfidine at room temperature between 15 and 30 degrees Celsius. Keep it away from heat, direct sunlight and moisture. Make sure that the drug is kept away from the reach of children and pets.
Side Effects & Interactions of Azulfidine
Less serious side effects of Azulfidine are:
- Stomach pain
- Mild stomach upset
- Nausea and vomiting
- Loss of appetite
Serious side effects of Azulfidine are:
- Swelling of the mouth, face and lips
- Severe allergic reactions such as rashes and hives
- Chest pain
- Bloody diarrhea
- Fever and chill
- Problems with hearing
- Pale stools
- Persistent dizziness and drowsiness
- Severe stomach pain
- Trouble sleeping
- Yellowing of the skin
- Dark urine
- Shortness of breath
- Unusual bleeding and bruising
If you experience the serious side effects, stop the medication and consult your doctor.
The following drugs may interact with Azulfidine:
You must inform your doctor about all the medications you take before start using Azulfidine. This includes over-the-counter drugs and herbal products. Don’t start, stop or change the dosage without consulting your doctor.
Warnings & Precautions of Azulfidine
You must not buy Azulfidine if you have:
- A history of blood disorders
- Folate deficiency anemia
- Blood or urine track blockage
- An allergy to any of the ingredients in Azulfidine
- An allergy to any drugs, foods, or other substances
- An allergy to salicylates
- Kidney disease
- Severe allergies
You must not buy Azulfidine if you are pregnant or planning to get pregnant. You must not use the drug if you are breastfeeding. You must not administer the medication in children below the age of 6 years.
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